Thu, 12 July 2012
JALA August 2012 Podcast: Performance Evaluation of 3D Polystyrene 96-Well Plates with Human Neural Stem Cells in a Calcium Assay
An HTS compatible 3D cell culture platform is generated by chemically “welding” polystyrene scaffolds into standard 2D polystyrene 96-well plates. The variability of scaffolds is minimized by introducing automation into the fabrication process.
Wed, 16 May 2012
JALA June 2012 Podast: Automation of Cell-Based Drug Absorption Assays in 96-Well Format Using Permeable Support Systems
In this report, Apparent Permeability (Papp) and Efflux data demonstrate how an automated procedure, when compared to manual processing, provides a method that is less variable and is capable of delivering a more accurate assessment of a compound’s absorption characteristics.